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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
BECN1
All Species:
42.12
Human Site:
Y256
Identified Species:
61.78
UniProt:
Q14457
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14457
NP_003757.1
450
51896
Y256
S
V
E
N
Q
M
R
Y
A
Q
T
Q
L
D
K
Chimpanzee
Pan troglodytes
XP_511522
450
51866
Y256
S
V
E
N
Q
M
R
Y
A
Q
T
Q
L
D
K
Rhesus Macaque
Macaca mulatta
XP_001111932
450
51890
Y256
S
V
E
N
Q
M
R
Y
A
Q
I
Q
L
D
K
Dog
Lupus familis
XP_537634
362
42279
S191
A
T
F
H
I
W
H
S
G
Q
F
G
T
I
N
Cat
Felis silvestris
Mouse
Mus musculus
O88597
448
51515
Y254
S
V
E
N
Q
V
R
Y
A
Q
I
Q
L
D
K
Rat
Rattus norvegicus
Q91XJ1
448
51538
Y254
S
V
E
N
Q
M
R
Y
A
Q
M
Q
L
D
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514527
394
45783
W221
F
N
A
T
F
H
I
W
H
S
G
Q
F
G
T
Chicken
Gallus gallus
Q5ZKS6
447
51416
Y253
S
V
E
N
Q
M
R
Y
A
Q
M
Q
L
D
K
Frog
Xenopus laevis
Q6GP52
445
51275
Y251
S
V
E
N
Q
M
R
Y
A
Q
I
Q
L
D
K
Zebra Danio
Brachydanio rerio
P13104
284
32704
K112
R
L
A
T
A
L
Q
K
L
E
E
A
E
K
A
Tiger Blowfish
Takifugu rubipres
NP_001032963
447
51199
Y253
S
V
D
N
Q
M
R
Y
C
Q
I
Q
L
D
R
Fruit Fly
Dros. melanogaster
Q9VCE1
422
48852
Y232
S
L
E
C
Q
I
A
Y
S
K
Q
Q
L
D
K
Honey Bee
Apis mellifera
XP_392365
430
49618
Y236
S
L
E
C
Q
L
A
Y
A
A
S
Q
L
E
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786368
415
47747
Y225
S
V
D
N
Q
L
K
Y
T
Q
T
Q
L
E
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9M367
517
58486
V293
A
I
L
A
K
I
E
V
S
Q
A
H
L
E
L
Baker's Yeast
Sacchar. cerevisiae
Q02948
557
63242
L309
S
L
K
L
Q
Y
E
L
S
L
N
Q
L
D
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
99.7
78.8
N.A.
97.3
97.3
N.A.
76.8
91.7
88.6
20
81.1
49.1
56.4
N.A.
57.5
Protein Similarity:
100
99.7
99.7
79.5
N.A.
98
98.2
N.A.
81.5
94.6
94.8
36.4
89.5
67.7
69.3
N.A.
71.5
P-Site Identity:
100
100
93.3
6.6
N.A.
86.6
93.3
N.A.
6.6
93.3
93.3
0
73.3
53.3
46.6
N.A.
60
P-Site Similarity:
100
100
93.3
20
N.A.
93.3
93.3
N.A.
13.3
93.3
93.3
26.6
86.6
80
80
N.A.
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
28
24.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
45.2
44.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
40
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
53.3
60
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
13
0
13
7
7
0
13
0
50
7
7
7
0
0
7
% A
% Cys:
0
0
0
13
0
0
0
0
7
0
0
0
0
0
0
% C
% Asp:
0
0
13
0
0
0
0
0
0
0
0
0
0
63
0
% D
% Glu:
0
0
57
0
0
0
13
0
0
7
7
0
7
19
0
% E
% Phe:
7
0
7
0
7
0
0
0
0
0
7
0
7
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
7
0
7
7
0
7
0
% G
% His:
0
0
0
7
0
7
7
0
7
0
0
7
0
0
0
% H
% Ile:
0
7
0
0
7
13
7
0
0
0
25
0
0
7
0
% I
% Lys:
0
0
7
0
7
0
7
7
0
7
0
0
0
7
57
% K
% Leu:
0
25
7
7
0
19
0
7
7
7
0
0
82
0
7
% L
% Met:
0
0
0
0
0
44
0
0
0
0
13
0
0
0
0
% M
% Asn:
0
7
0
57
0
0
0
0
0
0
7
0
0
0
7
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
75
0
7
0
0
69
7
82
0
0
0
% Q
% Arg:
7
0
0
0
0
0
50
0
0
0
0
0
0
0
19
% R
% Ser:
75
0
0
0
0
0
0
7
19
7
7
0
0
0
0
% S
% Thr:
0
7
0
13
0
0
0
0
7
0
19
0
7
0
7
% T
% Val:
0
57
0
0
0
7
0
7
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
7
0
7
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
7
0
69
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _